Anti-HIV-1 activity in human primary cells and Anti-HIV-1 RT inhibitory activity of extracts from the red seaweed Acanthophora spicifera
نویسندگان
چکیده
منابع مشابه
Investigation of anti-HIV activity, cytotoxicity and HIV integrase inhibitory activity of polyherbal formulation BH extracts
Background HIV integrase (IN) plays important roles at several steps, including viral DNA nuclear import, targeting viral DNA to host chromatin and integration. Identification of novel inhibitors of HIV Integrase has emerged as promising antiviral agents for the treatment of HIV/AIDS. Present work is to investigation of anti-HIV activity and HIV integrase inhibitory activity of various extracts...
متن کاملAnti-HIV-1 activity, protease inhibition and safety profile of extracts prepared from Rhus parviflora
BACKGROUND In the present study, extracts prepared from the leaves of Rhus parviflora Roxb. (Anacardiaceae) were evaluated for their anti-HIV activity, which have been traditionally used for the treatment of neurological disorders such as anxiety, insomnia and epilepsy. METHODS Aqueous and 50% ethanolic extracts prepared from leaves of the plant were tested for their cytotoxicity and anti-HIV...
متن کاملTriterpenoids from Schisandra lancifolia with anti-HIV-1 activity.
A new trinorcycloartane triterpenoid, lancifodilactone H (1), and a new A ring-secocycloartane triterpenoid, lancifoic acid A (2), together with a known compound, nigranoic acid (3), were isolated from the leaves and stems of Schisandra lancifolia. Their structures were elucidated by spectroscopic data analysis. Compound 1 features a biosynthetically modified seven-membered lactone ring, which ...
متن کاملAssessment of antioxidant activity, total phenolic content and in- vitro toxicity of Malaysian red seaweed, Acanthophora spicifera
Various extracts of local marine red algae, Acanthophora spicifera were evaluated for antioxidant activity, total phenolic content and in-vitro toxicity. The antioxidant activity was measured using DPPH (1, 1-diphenyl-2-picrylhidrazyl) method, while Folin-Ciocalteu method was used for the total phenolic content. The cytotoxicity of the extracts were evaluated using invitro brine shrimp lethalit...
متن کاملAnti-HIV-1 Activity of of Dimocarpus longan Lour. Extracts and the Main Chemical Content
The present study is carried out for the evaluation of anti-HIV-1 effect of Dimocarpus longan extracts and also the investigation of the phytoconstituents from the extracts. Chloroform, ethyl acetate and methanol 80% extracts of Dimocarpus longan aerial parts were tested for their antiHIV-1 activity using the syncytia formation assay. Ethyl acetate from Dimocarpus longan aerial parts extract ha...
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ژورنال
عنوان ژورنال: Journal of Medicinal Plants Research
سال: 2016
ISSN: 1996-0875
DOI: 10.5897/jmpr2016.6208